CD8 alpha anticorps (APC)
Aperçu rapide pour CD8 alpha anticorps (APC) (ABIN2567995)
Antigène
Voir toutes CD8 alpha (CD8A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Specificité
- The OKT8 monoclonal antibody specifically reacts with human CD8α molecule, a type I transmembrane glycoprotein of 32-34 kDa.
-
Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
-
Isotype
- IgG2a
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
-
Stock
- 4 °C
-
Stockage commentaire
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
-
-
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
-
Autre désignation
- CD8a
-
Sujet
- The OKT8 monoclonal antibody specifically reacts with human CD8α molecule, a type I transmembrane glycoprotein of 32-34 kDa. CD8α is a member of the Ig superfamily, expressed as a homodimer (CD8αα) or as a heterodimer (CD8αβ). CD8+ αβ T lymphocytes express both CD8αα and CD8αβ, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes.OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitope or block each other by steric hindrance.
-
ID gène
- 925
-
UniProt
- P01732
-
Pathways
- TCR Signaling
Antigène
-